Mass Spectrometry TLC/HPTLC Glass Plates from EMD Millipore

Mass Spectrometry TLC/HPTLC Glass Plates from EMD Millipore

Mass Spectrometry TLC/HPTLC Glass Plates from EMD Millipore

Description

Coupling TLC plates with mass spectrometry is a new field of high interest, which will contribute substantially to the progress of planar chromatography – both today and in the future. One particular advantage of TLC-MS is the flexibility in choosing mobile phases for separation, compared to HPLC-MS coupling, where certain mobile phases cannot be used (e.g. inorganic buffers cannot be used with HPLC-MS).

The techniques for coupling TLC with mass spectrometry can be divided into a) elution-based and b) desorption-based techniques. Both approaches are offline, and both are performed after the separation is completed and the plate dried. The sample transfer to the MS is fast and typically takes less than one minute.
  • With elution-based techniques, the analyte on the silica plate is dissolved in a solvent and transferred to the mass spectrometer in the liquid phase.
  • With desorption-based techniques, the analyte is vaporized from the silica and transferred to the MS in the gas phase. Vaporization techniques include gas beam, ion bombardment and MALDI (matrix-assisted laser desorption/ionization).

  • Detailed Specifications
  • ItemMass Spectrometry TLC/HPTLC Glass Plates
  • CompanyEMD Millipore
  • PriceGet Quote
  • Catalog Number1.00933.0001 / 1.00934.0001
  • QuantityEA
  • Plate Size(s)20 x 20 cm or 20 x 10 cm
EMD Millipore
EMD Millipore
290 Concord Road
Billerica, MA 01821
United States
Phone: (781) 533-6000