Similar to an HPLC instrument, capillary liquid chromatography pumps materials at high pressure through a separation column to identify, quantify, and purify compounds of interest. A capillary HPLC system includes a column, detector and solvent delivery system. However, capillary HPLC uses a smaller separation column (<0.3mm) than conventional HPLC which are usually made from fused silica capillaries. A capillary liquid chromatograph is used widely in biochemistry and analytical chemistry for unknown characterization, proteome investigations, and LC/MS. There are several advantages to capillary HPLC which includes taller peaks, improved detection limits, and less sample consumption.
Related categories: Micro HPLC / Nano HPLC System
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