Electrospray Ionization Mass Spectrometer (ESI MS)

Electrospray ionization mass spectrometers (ESI MS) use a so-called “soft” ionization technique that has found widespread use in biological mass spectrometry. Soft ionization techniques enable the ionization of large biological molecules (such as proteins) without fragmenting them, meaning they can be analyzed intact. In an electrospray ionization mass spectrometer, the molecules to be analyzed pass into the mass spectrometer in a fine spray, typically following chromatographic separation, whether via traditional liquid chromatography, HPLC, or nano-LC. As the spray emerges from the ESI source, the molecules are ionized by the nozzle’s electrically charged tip. As this mist travels and evaporates, electrostatic repulsion between like-charged ions ultimately forces the molecules apart. They then may be analyzed by a wide variety of mass analyzers, including quadrupoles, ion traps, time-of-flight, and Fourier transform-based instruments.

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1200 Series High Throughput LC/UV/MS System
  • Mass Analyzer: Quadrupole, TOF, Ion Trap, QQQ or Q-TOF
  • Ionization Method(s): ESI, APCI
  • Mass Range: m/z 2 to 3000 (depending on model)
  • Scanning Speed: up to 5250 u/sec
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6100 Series Single Quadrupole LC/MS
  • Mass Analyzer: Single Quadrupole
  • Ionization Method(s): ESI, APCI, APPI
  • Mass Range: Inquire
  • Scanning Speed: 10,000 amu/sec (Model 6140)
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  • Mass Analyzer: Time of Flight
  • Ionization Method(s): Electrospray (ESI)
  • Mass Range: 20 to 20,000 m/z
  • Scanning Speed: up to 40 spectra per sec.
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  • Mass Analyzer: Triple Quadrupole (QqQ)
  • Ionization Method(s): ESI, APCI, APPI
  • Mass Range: Inquire
  • Scanning Speed: up to 12,500 Da/sec
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  • Mass Analyzer: Quadrupole Time of Flight (QTOF)
  • Ionization Method(s): ESI, APCI, APPI and MALDI
  • Mass Range: m/z 20 to 20,000
  • Scanning Speed: up to 20 Spectra per sec.
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amaZon speed and amaZon speed ETD Trap Mass Spectrometers
  • Mass Analyzer: Ion Trap
  • Ionization Method(s): APCI, ESI
  • Mass Range: Inquire
  • Scanning Speed: 52,000 u/sec
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micrOTOF II Electrospray Ionization Mass Spectrometer
  • Mass Analyzer: TOF
  • Ionization Method(s): ESI, ESI-nano, APCI, APPI
  • Mass Range: 100 to 1000 Da
  • Scanning Speed: Inquire
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micrOTOF-Q III Electrospray Ionization Mass Spectrometer
  • Mass Analyzer: Qq-TOF
  • Ionization Method(s): ESI
  • Mass Range: 2ppm mass accuracy, low picogram sensitivity
  • Scanning Speed: Inquire
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LC/MS Purification System
  • Mass Analyzer: Single Quadrupole
  • Ionization Method(s): ESI, APCI
  • Mass Range: 50 to 3000 amu
  • Scanning Speed: up to 10,000 amu/sec
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LCMS-2020 Single Quadrupole Mass Spectrometer
  • Mass Analyzer: Single Quadrupole
  • Ionization Method(s): ESI and/or APCI
  • Mass Range: Inquire
  • Scanning Speed: 15,000 u/sec
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LCMS-8030 Triple Quadrupole LC/MS/MS Mass Spectrometer
  • Mass Analyzer: Molybdenum Hyperbolic Mass Filter with pre-rod
  • Ionization Method(s): ESI, APCI, DUIS
  • Mass Range: 10 to 2000 m/z
  • Scanning Speed: 15,000 u/sec (max)
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LCMS-8040 Triple Quadrupole LC/MS/MS Mass Spectrometer
  • Mass Analyzer: Triple Quadrupole
  • Ionization Method(s): ESI, APCI, Dual Ionization
  • Mass Range: Inquire
  • Scanning Speed: 15,000 u/sec.
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LCMS-8050 Triple Quadrupole LC/MS/MS Mass Spectrometer
  • Mass Analyzer: Inquire
  • Ionization Method(s): ESI
  • Mass Range: Inquire
  • Scanning Speed: 30,000 u/sec
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LCMS-IT-TOF Hybrid Mass Spectrometer
  • Mass Analyzer: MS/MS: Ion Trap/TOF
  • Ionization Method(s): APCI or ESI
  • Mass Range: Inquire
  • Scanning Speed: Inquire
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Other Companies that sell Electrospray Ionization Mass Spectrometer (ESI MS)

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  • Agilent Technologies
  • Bruker Daltonics
  • Gilson Inc
  • Shimadzu

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