Triple Quadrupole Mass Spectrometer (QqQ MS)

A triple-quadrupole mass spectrometer, also known as QqQ, is a tandem MS method in which the first and third quadrupoles act as mass filters and the second causes fragmentation of the analyte through interaction with a collision gas—it is a radiofrequency-only quadrupole, and can be used in either SIM or scan mode. The method can be used to obtain structural information or for quantitation. For structural mass spec, a common sequence is product ion scan, precursor ion scan, and neutral loss scan, followed by selected reaction monitoring (SRM) or multiple reaction monitoring (MRM). Increased selectivity, improved S/N, lower limits of quantitation, wider linear range, and improved accuracy are some of the benefits of this technique, which encompasses triple-quad LC-MS, GC-MS, GC-MSD, and ICP-MS. Although QqQ is a particularly useful method for all stages of pharmaceutical development, it is a reliable option for many applications, such as clinical research, food safety, forensics, environmental, and proteomics.

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5975C Series GC/MSD System

5975C Series GC/MSD System

Agilent Technologies

  • Ionization Method(s): EI, PCI, NCI
  • Mass Analyzer: Triple Quadrupole (Triple-Axis HED-EM)
  • Mass Range: up to1050 u
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5975E GC/MSD

5975E GC/MSD

Agilent Technologies

  • Ionization Method(s): Electron Ionization (EI)
  • Mass Analyzer: Monolithic Hyperbolic Quadrupole
  • Mass Range: up to 1050 u
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5975T Low Thermal Mass (LTM) Transportable GC/MSD
  • Ionization Method(s): Electron Ionization (EI)
  • Mass Analyzer: Monolithic Hyperbolic Quadrupole
  • Mass Range: up to 1050 u
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  • Ionization Method(s): ESI, APCI, APPI
  • Mass Analyzer: Triple Quadrupole (QqQ)
  • Mass Range: Inquire
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7000A Triple Quadrupole GC/MS Instrument
  • Ionization Method(s): EI, PCI, NCI
  • Mass Analyzer: Triple Quadrupole
  • Mass Range: 1.2 to 1,050 m/z
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LCMS-8030 Triple Quadrupole LC/MS/MS Mass Spectrometer
  • Ionization Method(s): ESI, APCI, DUIS
  • Mass Analyzer: Molybdenum Hyperbolic Mass Filter with pre-rod
  • Mass Range: 10 to 2000 m/z
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LCMS-8040 Triple Quadrupole LC/MS/MS Mass Spectrometer
  • Ionization Method(s): ESI, APCI, Dual Ionization
  • Mass Analyzer: Triple Quadrupole
  • Mass Range: Inquire
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LCMS-8050 Triple Quadrupole LC/MS/MS Mass Spectrometer
  • Ionization Method(s): ESI
  • Mass Analyzer: Inquire
  • Mass Range: Inquire
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