Gas chromatograph mass spectrometers (GC MS) are to volatile chemical compounds what liquid chromatography (LC) MS systems are to materials in solution: they separate and analyze gas-phase molecules.
How do GC MS Instruments work?
In LC, compounds are fractionated based on their differential affinity for the separation’s mobile (liquid) and stationary phases (column packing material). In GC, heated, volatile compounds are injected into a flowing gas stream and separated as that stream flows through a long hollow tube (sometimes tens of meters in length) coated with a stationary phase material. In GC MS chromatography, the fractionated compounds are then ionized (typically by electron ionization) and injected into the mass spec analyzer, most commonly a single quadrupole (though triple quadrupoles and time-of-flight analyzers are also available).
What are GC MS Instruments Used For?
Gas chromatograph mass spectrometers are generally used to analyze small, relatively non-polar compounds, and are widely used in forensics, food safety, environmental monitoring, and petrochemicals, among others.
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LECO
- Electron Ionization (EI)
- Time of Flight
- Inquire
JEOL USA, Inc.
- El, CI, PI
- Single quadrupole
- 1 to 1022 u
LECO
- Electron Ionization
- Time of Flight
- Inquire
Shimadzu
- Chemical Ionization, Negative Chemical Ionization
- Quadrupole Mass Analyzer
- Inquire
LECO
- Electron Ionization
- Time of Flight
- Inquire
Thermo Fisher Scientific
- Inquire
- Inquire
- m/z 30 to 3,000
Thermo Fisher Scientific
- Full range of Ionization Modes Available: EI, CI, and FD/FI
- Ultra-high precision toroidal electrostatic analyzer and magnetic analyzer
- 2 to 6000 m/z
SCION Instruments
- Electron Ionization (EI) as standard. Optional ionization modes: Chemical Ionization (CI) including PCI and NCI
- Inquire
- 1 to 1200Da
Shimadzu
- EI, CI, NCI
- Metal quadrupole with pre-rod
- 1.5 to 1090 m/z
Thermo Fisher Scientific
- EI/PCI/NCI
- High-field Orbitrap mass analyzer
- m/z 30 to 3,000
Shimadzu
- Electron Ionization (EI)
- Quadrupole
- 1.5 to 1000 m/z
SCION Instruments
- Electron Ionization (EI) as standard
- Triple quadrupole
- 1 to 1200Da
JEOL USA, Inc.
- EI / PI / CI / FI / FD / DCI / DEI
- Reflectron Time-of-Flight Mass Spectrometer, Direct MS mode
- 6000 m/z
Shimadzu
- Inquire
- Single quadrupole
- Inquire
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