Shimadzu Scientific Instruments offers the PPSQ-51A single reactor and PPSQ-53A triple reactor gradient system protein sequencers. The instruments provide users with higher sensitivity and more reliable analysis of N-terminal amino acid sequences through automated Edman degradation. In addition, they provide an added level of flexibility in being able to detect and identify additional rare and modified amino acids and are FDA 21 CFR Part 11 compliant when used with the LabSolutions analysis data system. The protein sequencers perform sequence analysis at substantially lower levels using gradient separation and a flow cell that enables high-sensitivity detection of PTH-amino acids. These systems have high analysis stability because they are equipped with a high-performance detector and a solvent delivery pump that provides high pumping performance.