Low-Adhesion Plates for Retinal Organoids

AMSBIO Lipidure-COAT plates help culture physiologically functional, light-responsive retinal organoids. The coated plates use MPC (2-methacryloyloxtethyl phosphorylcholine), a biocompatible synthetic polymer with the same structure as the phosphorylcholine polar bases that form cell membranes. Due to the high biocompatibility of this coating, cells will not adhere to the surface of the coated plates or dishes. Different well-shapes (U, V, and flat-bottom) can be used to control size, position, and the density of organoid culture. Studies have shown that Lipidure coated microplates promote the formation of a single spheroid in concave (U- or V-shaped) wells, while other plates lead to the formation of satellite spheroids, indicating that a higher degree of cell adhesion is taking place.

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