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YNT-185 ● 2HCl
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Wako now supplies YNT-185 • 2HCl, a non-peptide orexin receptor 2 (OX2R) agonist. Orexins are a family of neuropeptides secreted by orexin-producing nerve present in the hypothalamus. OX2R is involved in sleep-wake regulation. Orexin deficiency in the brain causes narcolepsy. Learn more
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Industry News
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Team Modifies NRPS Enzymes to Produce Peptides Learn More
IR Spectroscopy Blood Test Detects Biochemical Changes Induced by... Learn More
Circadian Clock Suppresses Tumors Learn More
Study Elucidates Intercellular Transmission of ERK Activity Learn More
Computer Model Shows How Immune System Reacts to hCMV Peptides to... Learn More
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Featured Articles
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Validation of an Image-Based 3D Natural Killer Cell Mediated Cytotoxicity Assay
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An in vitro model for Natural Killer (NK) cell mediated cytotoxicity was developed using a collagen-based scaffold 3D cell culture technology. This technology induced HCT116 cells to aggregate into tumoroids over time which became the target cells during the cytotoxicity assay. Cytotoxicity was assessed by both phosphatidyl serine exposure (apoptosis) and plasma membrane rupture (necrosis) using fully automated workflows. Cytotoxicity was quantified using NK cells alone and with IL-2 stimulation, where a significant increase of cytotoxicity was evident. Cytotoxicity with this model was ... . Learn more
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Have fun with our BERTHOLD XMAS QUIZ!
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The first Advent candle has been lit. The Christmas markets have opened. All that´s missing now for an exciting pre-Christmas season is the BERTHOLD XMAS QUIZ making your Christmas wishes come true:
Win one of our exciting technology prizes every ... . Learn more
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