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Detecting Cannabinoids in Industrial Hemp Using Single Quadrupole LC-MS
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Liquid chromatography-mass spectrometry (LC-MS) is becoming increasingly recognized for the quantitative determination of cannabinoids, because it provides higher sensitivity, specificity and mass identification. We developed a quantitative LC-MS method using simultaneous in-source fragmentation (SID) for the identification of 16 cannabinoids, including ?9-tetrahydrocannabinol (?9-THC), ?8-tetrahydrocannabinol (?8-THC), cannabidiol (CBD), cannabigerol (CBG), cannabinol (CBN), cannabicyclol (CBL) and their respective acidic forms. We used selected ion monitoring (SIM) for quantitation and ... . Learn more
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