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Guide: The Kilogram Redefinition
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To ensure stability of the kilogram's unit of mass, a new definition was derived. This guide details the history and process of redefining the kilogram and what it means for the future of this unit of measurement. Learn more
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Featured Articles
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COVID-19 Vaccine Developments: Emerging Technologies, Safety Concerns and Antibody-Dependent Enhancement
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Since the SARS-CoV-2 genome had been sequenced, researchers around the globe have been racing to develop a vaccine for COVID-19. Traditional vaccine development can take up to 10 years to produce a safe and effective vaccine. Due to the obvious safety concerns presented by the novel coronavirus (SARS-CoV-2), vaccine development has been deemed paramount to global security, and timelines for an effective vaccine are estimated to be 12-18 months. There are nearly 100 vaccine candidates under review at this very moment, however, many are still at the conceptual stage. Leading the pack are several... . Learn more
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Optimizing DLS Measurements for Protein Characterization
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Many common globular proteins are very small in hydrodynamic size, with monomers rarely greater than 10 nm. Protein aggregates can easily reach large sizes, on the order of several hundred nm or larger, which complicate this already challenging measurement. In this scenario scattering from aggregated protein easily dominates the signal of free, or monomeric protein. This principle is demonstrated with a pharmaceutically relevant protein, monoclonal antibody, mAb, studied in both its monomeric and aggregated states.. Learn more
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