Description
5(6)-EET-d11 contains 11 deuterium atoms at the 16, 16', 17, 17', 18, 18',19, 19',20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of 5(6)-EET bcy GC- or LC-mass spectrometry (MS). 5(6)-EET is biosynthesized in rat and rabbit liver microsomes by cCYP450. In neuroendocrine cells, such as the anterior pituitary and pancreatic islet, 5(6)-EET has been implicated in the mobilization of Ca2+ and hormone secretion.(±)5(6)-EET-d11is an internal standard of 5(6)-EET bcy GC- or LC-mass spectrometry