Description
DescriptionNon-explosive replacement for HOBt and HOAt with at least comparable performance to HOAtOutperforms HOAt in sterically demanding peptide bond formationsCompatible with carbodiimide-mediated; solution and solid phase peptide coupling;Less epimerization than HOBt in fragment condensation reactionsK-salt especially useful in peptide coupling on mild acid-labile resins such as 2-chlorotrityl; leading to minimal to no cleavage of the peptide from the resin due to its more alkaline characterK-salt has a higher melting point than OxymaPure