Description
DescriptionGramicidin A is a linear pentadecapeptide antibiotic produced byBacillus brevis. The transmembrane protein contains a left-handed helix with alternating L and D residues.Chemical structure: peptideGramicidin A is used for studies on bacterial cell wall permeabilization and monovalent cation channel formation. Gramicidin has also been shown to inhibit transcription of T7 phage DNA, inhibit membrane-bound epidennal adenosine triphosphatase, suppress human lymphocyte blastogenesisin vitroand prolong heart allograft survival in the rat model