Description
Oxalyl chloride is a commonly used chlorinating reagent that can be prepared by the reaction of oxalic acid and phosphorus pentachloride.ApplicationOxalyl chloride may be used in the following processes: Preparation of Mosher′s acid chloride by reacting with Mosher′s acid in the presence of DMF. Activation of dimethyl sulfoxide for use in the oxidation of long-chain alcohols to carbonyls. Activation of α-keto carboxylic acids and N -heterocyclic carboxylic acids for alkynylation to form ynediones and N -heterocyclic ynones, respectively. Suitable for the synthesis of acid chlorides used to produce liquid crystals. Reactant involved in: Synthesis of N -heterocyclic ynones and ynediones, used to activate carboxylic acids Chlorination and halogenation Three-component [3+2] cycloadditions Reactions with organostannanes Synthesis of cyclopentenones Carbonylations, used as a carbonyl synthon