Description
(E)-2′-Hydroxychalcone is a chalcone derivative. Chalcone derivatives have exhibited unexpectedly good activity as angiogenesis inhibitors. Experimental results indicate that the flavonoids chalcone, 2-hydroxychalcone, and quercetin present in our daily foods have an inhibitory effect on oral carcinogenesis initiated with 4-NQO, and such a modifying effect may be related partly to the suppression of cell proliferation