Description
2-(4′-(dimethylamino)phenyl)-6-methyl-benzothiazole is an uncharged derivative of Thioflavin-T, displaying 6-fold higher affinity than Thioflavin-T, and shows high affinity for amyloid deposits [Ki = 143 nM for Ab(1-40)]. It can cross the blood brain barrier, and stains both plaques and neurofibrillary tangles in post mortem Alzheimer's disease brain