Description
Product DescriptionCoenzyme A (CoA) is synthesized from phosphopantothenate by the action of enzyme pantothenate kinase and is the master regulator. Product ApplicationCoenzyme A trilithium salt has been used: in standard curve generation in the kinetic assay of acetyltransferase Gcn5 acylation as a cofactor in JNADH and JNADPH production assay in the labeling of Alexa647 (AF647) probeBiochemical and physiological mechanismsCoenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. Acyl CoA accumulation is implicated in metabolic disorders and may indirectly lead to the pathogenesis associated with carbon-induced mitochondrial stress heart failure, diabetes and obesity