Description
Propargyl-PEG3-Ms is a PEG derivative containing a propargyl group and a Ms group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. A mesyl is a better leaving group compared to a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media