Description
Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) proteinin elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatographyas a component of homogenization buffer for the purification of phagosomal compartments from dendritic cellsExcellent for buffers in the range of pH 6.2-7.8