Description
N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) is a branched PEG derivative with two terminal propargyl groups and a t-butyl ester. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under mild acidic conditions