(1R,2R)-ML-SI3 from Aladdin Scientific Corporation

(1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 ( IC 50 values of 1.6 and 2.3 µM) and a weak inhibitor ( IC 50 12.5 µM) of TRPML3Form:SolidIC50& Target:TRPML1 1.6 µM (IC 50 ) TRPML2 2.3 µM (IC 50 ) TRPML3 12.5 µM (IC 50 )