Description
(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 µM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 µM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1]