Description
20S Proteasome activator 1 is a potent 20S proteasome activator with EC200 values of 0.3 µM, 0.7 µM and 1.8 µM for trypsin-like site, chymotrypsin-like site and caspase-like site. 20S Proteasome activator 1 translates well in a cellular system, preventing the accumulation of the pathogenic A53T mutant of α-synuclein. 20S Proteasome activator 1 can be used for researching neurodegenerative diseases[1]