Description
Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 µM), caspases-5 (IC50 of 329 nM), and caspases-11, but not the apoptotic caspases such as caspase-3[1]