Description
7-Methylguanine is an orally active and competitive PARP-1 inhibitor with a Ki value of 61 µM. 7-Methylguanine is a metabolite of nucleic acids. 7-Methylguanine has anticancer activity against uterine sarcoma and colon adenocarcinoma. 7-Methylguanine is used as a probe for protein-DNA interactions[1][2][3][4][5][6]