AZ 11645373 from MedChemExpress

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MedChemExpress for
AZ 11645373

Description

AZ11645373 is a highly selective and potent antagonist at human but not rat P2X7 receptors，AZ11645373 inhibits ATP-evoked IL-1β release from lipopolysaccharide-activated THP-1 cells, with an IC50 value of 90 nM[1]