5-Iodo-indirubin-3'-monoxime from MedChemExpress

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5-Iodo-indirubin-3'-monoxime

Description

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively[1]