(1R,2R)-ML-SI3 from MedChemExpress

(1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of three isoforms of TRPML. (1R,2R)-ML-SI3 inhibits TRPMLs with IC50s of 1.6 µM (TRPML1), 2.3 µM (TRPML2), and 12.5 µM (TRPML3), respectively[1]