Description
The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with stable homozygous transformation with Cys112 (TGC) from Arg112 (CGC) and Cys158 (TGC) from Arg158 (CGC) in APOE gene. The morphology of this human iPS cell line is similar to Human ES cells are the same. They also express pluripotency markers TRA-1-60, SSEA-3 and Oct4, and show strong endogenous alkaline phosphatase activity.
feature:
Derived from a single iPSC clone
Have the same genetic background
Ready-made-simply thaw the cells and inoculate them in a serum-free, feeder-free culture
No genetic modification and no virus
Shows the expression of pluripotency markers and endogenous alkaline phosphatase activity