Description
Mice microglia (MMcg) are primary mouse microglia derived from CD1 mouse brains on the first day after birth. When resurrected, inoculated and cultured under the recommended conditions, MMcg forms adherents bring up.
Microglia originate from hematopoietic stem cells in the bone marrow and are resident macrophages in the central nervous system (CNS). Due to the presence of the blood-brain barrier, they are separated from the rest of the body. Microglia actively investigate the surrounding area and respond by removing damaged nerve cells, plaques and infectious agents. Because microglia have the function of immune response and maintaining homeostasis in the central nervous system, they are related to neurodevelopment, central nervous system plasticity and repair, neuroinflammation, aging and neurodegeneration, neuropathic pain and infection.