Description
Creative Biolabs's Human iPSC-Derived Motor Neuron Progenitors from a healthy male donor carrying C9orf72 hexanucleotide expansion. The repeat expansion of the parental iPSC line of the motor neuron progenitor was determined by Southern blot.
C9orf72 is present in ~ 40% of familial ALS and 8-10 % of sporadic ALS. It is the most common mutation related to ALS - far more common than SOD1 or TDP-43.