Description
Apoptin-derived peptide acetate is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide acetate promotes apoptosis and necroptosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide acetate inhibits the invasion and migration of cancer cells, and inhibits the expression and phosphorylation of the subunit p85 of PI3K, which further inhibits the PI3K/AKT pathway involved in the development of gastric cancer[1]