Description
CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst1) with a Ki of 52 nM[1]. CH 275 acts as a potent and selective sst1 agonist (IC50=30.9 nM) and also displays IC50 values of 345 nM, >1 µM, >10 µM, >10 µM for human sst3, sst4, sst2 and sst5, respectively[2]. CH 275 can be used for the research of alzheimer’s disease[3]