Description
PEP1 is an amphipathic α-helical peptide containing 31 residues. PEP1 exhibits a concentration-dependent interaction with POPC-supported lipid bilayers (SLBs): at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface, leading to constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used in studies on the mechanism of membrane-peptide interactions[1]