Analysis of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Samples Per EPA Method 1633

Friday, May 10, 2024

United States (US) Environmental Protection Agency (EPA) Method 16331 is an analysis method for the detection and quantitation of per- and polyfluoroalkyl substances (PFAS) in many matrices including wastewater, soils, solids, and tissues. A previous application note used existing solid phase extraction (SPE) technology and highlighted Agilent instrument performance. This application note addresses PFAS testing in aqueous wastewater samples per the EPA Method 1633 using Agilent Bond Elut PFAS WAX SPE cartridges. The instrumentation for analysis utilized the Agilent 1290 Infinity II liquid chromatograph (LC) system coupled to the Agilent 6470 triple quadrupole (TQ) mass spectrometer (LC/TQ). The study verified method performance in terms of analyte extraction recoveries, sensitivity (method detection limits), and reproducibility. Download now to learn more.

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