Artel Highlights New Uses of the MVS to Improve Assay Performance

Westbrook, ME (April 23, 2012) – Artel, the worldwide leader in laboratory liquid handling quality assurance and performance verification, is introducing two new applications that use the Artel MVS® Multichannel Verification System to verify key steps in the assay workflow that are critical to gaining reliable results.

One of the new applications employs the MVS to ensure complete mixing of solutions in microtiter plates, which is critical for assay effectiveness and repeatability, especially when assays require further dilutions of mixed samples. Liquids dispensed into microtiter plates are often assumed to have been mixed thoroughly through simple diffusion, multiple aspirate and dispense cycles with a liquid handler, or after a cursory shaking of the plate. The application note highlights how inefficient these methods can be and provides scientists with a methodology to measure and optimize the efficiency of the liquid mixing techniques they employ in their laboratories to give them greater confidence in their assay results.

The other new application uses the MVS to provide a method to measure the effectiveness of plate washing steps. Failure to remove residual liquids from microtiter plates can lead to incorrect measurements and potentially lead to faulty and misinterpreted results. While existing methods to verify plate washer effectiveness are time consuming and tedious, the MVS application can be used to rapidly verify washer effectiveness to remove this source of assay error.

"Artel is dedicated to helping scientists trust their results and these new applications notes describe how the MVS can be used to optimize and verify the performance of a number of critical steps in the assay workflow," said George Rodrigues, PhD, Senior Scientist, Artel. "We continues to guide laboratory professionals on how to gain advantage of the MVS technology for quality assurance across all their liquid handling operations."

The MVS utilizes Artel’s proprietary Ratiometric Photometry™ technology to measure the accuracy and precision of any liquid handling device with up to 384 channels. The system is commonly used in drug discovery laboratories to improve screening efficiency as well as for assay development and manufacturing so laboratories can maintain compliance and data integrity.

To access Artel’s application notes and learn more about the impact of liquid handling quality in the laboratory, please visit http://www.artel-usa.com/application_notes.aspx.

About Artel
Artel is the world-leading liquid handling quality assurance expert. The company specializes in solving liquid handling quality, productivity and compliance challenges for life science laboratories. Its customers include pharmaceutical and biotechnology companies, and regulatory bodies, as well as laboratories in the university, clinical, diagnostic, forensic, public health and environmental sectors.

Since 1982, Artel has been using its expertise and range of ratiometric photometry-based systems to improve laboratory quality, productivity and compliance by ensuring liquid handling instruments generate reliable assay data and comply with regulatory demands. Artel also provides a broad and fully customizable range of quality assurance support, training and consultation services including Liquid Handler Performance Verification services for automated laboratories, and on-site Pipetting Technique Training and Quality Management Certification for pipette users and laboratory managers.

World -leading organizations such as Amgen, ARUP, Bristol-Myers Squibb, Celgene, Centers for Disease Control, DuPont, Eli Lilly, FBI, Genentech, Genomic Health, Mayo Clinic, Memorial Sloan-Kettering Cancer Center, Merck, Pfizer, Procter & Gamble and the U.S. FDA depend on Artel technology to help them meet their objectives for quality and productivity.

For more information,
Artel at 25 Bradley Drive,
Westbrook,
ME 04092;
Tel: 207-854-0860;
Fax: 207-854-0867;
Website: www.artel-usa.com.