SAN DIEGO, CA Feb. 11, 2013 - Interactive Biosoftware, developer of Alamut, the world's original mutation interpretation software, unveils its first upgrade to Alamut-HT--Alamut-HT 1.1, a comprehensive human genomic variation annotation and interpretation solution.
With version 1.1, Alamut-HT now integrates HGMD (the Human Gene Mutation Database) and NHLBI GO Exome Sequencing Project (ESP) data. External annotations supplied in variant annotation files can now be integrated in the output, and variants can be filtered by regions of interest. Unannotated variants can now be reported in the annotation output file, unless an output-only option is selected. As a high throughput annotation engine for next-generation sequencing (NGS) analysis, Alamut-HT 1.1 is designed for intensive variant analysis workflows. It enriches raw NGS variants with dozens of attributes, including effects on human genes, detailed single nucleotide polymorphisms (SNP) information, and missense and splicing predictions.
"Alamut-HT's splicing predictions are a unique feature not included by any other software on the market," said André Blavier, Founder and CEO of Interactive Biosoftware. "Another distinctive aspect of the software is that it can be deployed either as a cloud-based client-server system or as a full standalone installation that includes an automatically updatable database. This takes Alamut's capabilities to a new level for the benefit of the end-user."
Alamut-HT 1.1 is complementary software to Alamut, which is a rich graphical application for variant interpretation that is used to greatly improve the working process of researchers and geneticists. The upgraded Alamut-HT1.1 brings even greater efficiency to the researcher with its comprehensive, adaptable, and scalable capabilities.
"The future of genomics lies in next-generation sequencing. We intend to be an integral part of that future," said Blavier.
About Alamut: Alamut is a decision-support software and client server application that integrates genetic information from different sources in one convenient environment to describe variants using HGVS nomenclature and help interpret their pathogenic status. Dedicated to mutation diagnostics, Alamut is used by clinical and research molecular laboratories worldwide. Alamut enables researchers to access data without in-house bioinformatics. The data is curated and reliable, and feedback shows that it increases users' confidence in their reports. Alamut is the software of choice for leading university medical centers, hospitals, and private human genome laboratories. It is currently being used by more than 200 entities in 25 countries on five continents around the world.
About Interactive Biosoftware: Established in April 2007, Interactive Biosoftware (IBS) is a software company located in Rouen, France. IBS provides geneticists and researchers with the most sophisticated, easy-to-use and reliable software. The company is managed by a core of five seasoned professionals and influenced by academics specializing in the medical field. The company engineers and manufactures world-renowned decision software, Alamut-HT 1.1 and Alamut 2.2, which aids geneticists and researchers in interpreting mutations and variances in human genes. The software makes appropriate diagnostics, surveillance, and information-sharing between and across all tiers of human genome research. IBS strives to play an active role in the process of understanding and finding solutions for society's most devastating diseases. It has established significant relations in Western Europe as well as in the U.S. with Harvard University, Columbia University, and Mayo Clinic. For more information please visit www.interactive-biosoftware.com or contact us at [email protected] ; (866) 828-9668.