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| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Phospho Tau (181P) ELISA | Human TPMT (Thiopurine S-methyltransferase) ELISA | S100B ELISA Assay | Triiodothyronine (Free) ELISA Assay | Vitamin D, 25-OH Total RIA CT Assay |
| Citations | | | | | |
| Catalog Number | 27812 | IB08001 | 708-85 | IB79136 | KIR1971 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | The Human TPMT (Thiopurine S-methyltransferase) ELISA has been designed for the detection of TPMT in serum, plasma, tissue homogenates and other biological fluids. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay (ELISA) for the determination of S100B (S100A1B + S100BB) in serum. For research use only, not for use in diagnostic procedures. | Solid phase competitive enzyme immunoassay (ELISA) for the quantitative determination of Free Triiodothyronine (fT3) concentration in human serum. FDA exempt, can be used for in-vitro diagnostics. | Radioimmunoassay (RIA) for the determination of 25-hydroxyvitamin D3 and D2 (25-OH-D3 and 25-OH-D2) in serum. For research use only, not for use in diagnostic procedures. |
| Detection Target | Normetanephrine | Pancreatic Polypeptide | Complement System Alternative Pathway | Amyloid Beta (1-42) | LRG |
| Sample Type | Blood Plasma | Serum | Serum | Blood Plasma, CSF, Serum, Cell Culture Media, Extract from Brain Tissue | Serum, Blood Plasma, Urine, CSF |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Radio Immuno Assay (RIA) |
| Detection Range | 0 / 2.2 - 143 pg/mL | 0 / 3.125 - 200ng/ml | 10 to 3500 ng/L | 0.9 to 19.0 pg/mL | 10 to 100 ng/mL |
| Sensitivity | 23 pg/mL | 3 pmol/L | Inquire | 4.03 pg/mL | 0.17 ng/mL |
| Assay Time | Overnight + 1 hour (incubation) | 3 hour, 30 min. total incubation time. | 3 hrs 30 mins (incubation) | 1 hr 20 mins (incubation) | 3 hrs (incubation) |
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