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| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Phospho Tau (181P) ELISA | Anti-Tocilizumab (Actemra®) ELISA | APP-Beta-CTF ELISA Assay | Bordetella pertussis IgM ELISA | Human TPMT (Thiopurine S-methyltransferase) ELISA |
| Citations | | | | | |
| Catalog Number | 27812 | TM09021 | 27776 | IB79851 | IB08001 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | Enzyme immunoassay (ELISA) test kit for the determination of free antibodies directed against the drug Tocilizumab (Actemra®) in serum and plasma. For research use only, not for use in diagnostic procedures. | Solid phase sandwich ELISA for the determination of Human APP ßCTF in cell lysate. For research use only, not for use in diagnostic procedures. | The Bordetella pertussis IgM ELISA is intended for the determination of IgM class antibodies against Bordetella pertussis in human serum or plasma (citrate, heparin). For research use only - not for use in diagnostic procedures. | The Human TPMT (Thiopurine S-methyltransferase) ELISA has been designed for the detection of TPMT in serum, plasma, tissue homogenates and other biological fluids. For research use only, not for use in diagnostic procedures. |
| Detection Target | Normetanephrine | S100B | Clostridium tetani toxin IgG | Serotonin | Pancreatic Polypeptide |
| Sample Type | Blood Plasma | Serum | Serum, Blood Plasma | Multiple | Serum |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Detection Range | 0 / 2.2 - 143 pg/mL | 0 / 6 to 200 ng/mL | 0.19 to 12 pmol/L | A cut-off control is used for the interpretation of results. | 0 / 3.125 - 200ng/ml |
| Sensitivity | 23 pg/mL | Inquire | 99.22% (95% confidence interval: 95.76% - 99.98%) | 0.005 ng/mL x Correction Factor based upon volume of sample used. | 3 pmol/L |
| Assay Time | Overnight + 1 hour (incubation) | 2 hours, 10 min. total incubation time. | Overnight + 1 hr 30 mins (incubation) | 1 hr 45 mins (incubation) | 3 hour, 30 min. total incubation time. |
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