|  | | | | |
| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Phospho Tau (181P) ELISA | ACTH ELISA Assay | GABA ELISA Assay | Parvovirus B19 IgM ELISA Assay | Triiodothyronine (Free) ELISA Assay |
| Citations | | | | | |
| Catalog Number | 27812 | BM7023 | IB89150R | IB79807 | IB79136 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | Enzyme-linked immunosorbent assay (ELISA) for the determination of ACTH (Adrenocorticotropic Hormone) in human plasma. 510(k) cleared. This assay is intended for in-vitro diagnostic use. | Enzyme Immunoassay (ELISA) for the determination of Gamma-aminobutyric acid (GABA) in human plasma, serum, and urine. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay (ELISA) for the determination of IgM-class antibodies to Parvovirus B19 in serum. For research use only, not for use in diagnostic procedures. | Solid phase competitive enzyme immunoassay (ELISA) for the quantitative determination of Free Triiodothyronine (fT3) concentration in human serum. FDA exempt, can be used for in-vitro diagnostics. |
| Detection Target | Normetanephrine | Amyloid Beta (1-x) | Free Triiodothyronine (T3) | Endothelin-1 (Big) | Amyloid Beta (1-42) |
| Sample Type | Blood Plasma | Blood Plasma, CSF, Serum, Cell Culture Media, Extract from Brain Tissue | Serum and EDTA Plasma. | Serum, Blood Plasma, Supernatent of Cell Culture Media, Extracted Solution from Tissue | Blood Plasma, CSF, Serum, Cell Culture Media, Extract from Brain Tissue |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Detection Range | 0 / 2.2 - 143 pg/mL | 5 to 165 pg/mL | 75 to 7500 ng/mL | Inquire | 0.9 to 19.0 pg/mL |
| Sensitivity | 23 pg/mL | 3.55 pg/mL | 0.5 pmol/L | 0.30 pg/mL | 4.03 pg/mL |
| Assay Time | Overnight + 1 hour (incubation) | 4 hrs 30 mins (incubation) | 6 hrs (incubation) | 1 hr 45 mins (incubation) | 1 hr 20 mins (incubation) |
| Get Quote | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |