Assay kits are used to carry out analyses in a broad scope of applications including the study of targets such as drugs, molecules, disease pathways, chemical elements or compounds, and organisms. They are a routine procedure in the modern pharmaceutical, medical and forensic world as well as research and university laboratories around the globe. Assay kits come with all the necessary reagents, instructions and protocols for fast and efficient processing, allowing for repeatable results.
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| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Phospho Tau (181P) ELISA | Amyloid Beta (1-x) ELISA Assay | C5a ELISA Assay | Estrone ELISA Assay | Mac-2 binding protein (Mac-2bp) ELISA Assay |
| Citations | | | | | |
| Catalog Number | 27812 | 27729 | IB79153 | IB79312 | 27362 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | Solid phase sandwich ELISA for the determination of human Aß (1-x) in EDTA-plasma, cerebrospinal fluids, serum, cell culture media or the extract from brain tissue. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay for the determination of Anaphylatoxin C5a in human plasma or urine. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay (ELISA) for the determination of Estrone in saliva. For research use only, not for use in diagnostic procedures. | Solid phase sandwich ELISA for the determination of human Mac-2bp in serum, EDTA-plasma and cell culture media. For research use only, not for use in diagnostic procedures. |
| Detection Target | Normetanephrine | BACE1 | DPP4 / CD26 | ACTH | Anti-Adalimumab (Humira®) |
| Sample Type | Blood Plasma | Brain Extracts, Cultured Cell Lysate | Serum, Blood Plasma, Urine, CSF | Blood Plasma | Serum and plasma. |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Detection Range | 0 / 2.2 - 143 pg/mL | 7.81 to 500 pg/mL | 0.1 to 10 µg/L | 10 to 300 pg/mL | 0.78 to 100 ng/mL |
| Sensitivity | 23 pg/mL | 0.16 ng/mL | 8.58 pg/mL | 1.16 pg/mL | 5 ng/mL |
| Assay Time | Overnight + 1 hour (incubation) | Overnight + 1 hr 30 mins (incubation) | 50 mins (incubation) | 1 hr 15 mins (incubation) | 2 hrs (incubation) |
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