Assay kits are used to carry out analyses in a broad scope of applications including the study of targets such as drugs, molecules, disease pathways, chemical elements or compounds, and organisms. They are a routine procedure in the modern pharmaceutical, medical and forensic world as well as research and university laboratories around the globe. Assay kits come with all the necessary reagents, instructions and protocols for fast and efficient processing, allowing for repeatable results.
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| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Phospho Tau (181P) ELISA | NSE ELISA Assay | Pregnenolone ELISA Assay | SHBG ELISA Assay | Vitamin D, 25-OH Total RIA CT Assay |
| Citations | | | | | |
| Catalog Number | 27812 | 420-85 | IB59107 | IB79131 | KIR1971 |
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| Description | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | Enzyme immunoassay (ELISA) for the determination of NSE (Neuron-Specific Enolase) in human serum. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay (ELISA) for the direct quantitative determination of Pregnenolone in human serum. FDA exempt, for in vitro diagnostic use only. | Enzyme immunoassay (ELISA) for the determination of Sex-Hormone-Binding Globulin (SHBG) in serum and heparin plasma. For research use only, not for use in diagnostic procedures. | Radioimmunoassay (RIA) for the determination of 25-hydroxyvitamin D3 and D2 (25-OH-D3 and 25-OH-D2) in serum. For research use only, not for use in diagnostic procedures. |
| Detection Target | Normetanephrine | Complement Factor P (Properdin) | Adrenaline | Dopamine | LRG |
| Sample Type | Blood Plasma | Human serum or EDTA plasma. | Blood Plasma, Urine | Blood Plasma, Urine | Serum, Blood Plasma, Urine, CSF |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Radio Immuno Assay (RIA) |
| Detection Range | 0 / 2.2 - 143 pg/mL | 7.5 to 138.0 µg/L | 0.1 to 25.6 ng/mL | 4 to 260 nmol/L | 10 to 100 ng/mL |
| Sensitivity | 23 pg/mL | Inquire | Urine: 0.9 ng/mL. Plasma: 0.01 pg/mL. | Urine: 2.5 ng/mL. Plasma: 49.0 pg/mL. | 0.17 ng/mL |
| Assay Time | Overnight + 1 hour (incubation) | 1 hrs 30 mins (incubation) | 1 hr 15 mins (incubation) | 1 hr (incubation) | 3 hrs (incubation) |
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