Assay kits are used to carry out analyses in a broad scope of applications including the study of targets such as drugs, molecules, disease pathways, chemical elements or compounds, and organisms. They are a routine procedure in the modern pharmaceutical, medical and forensic world as well as research and university laboratories around the globe. Assay kits come with all the necessary reagents, instructions and protocols for fast and efficient processing, allowing for repeatable results.
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| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Phospho Tau (181P) ELISA | Angiotensin II RIA Assay | Complement C4d ELISA | Insulin ELISA Assay | SHBG ELISA Assay |
| Citations | | | | | |
| Catalog Number | 27812 | RB320 US | COMPL C4d RUO | IB79167 | IB79131 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | Radioimmunoassay (RIA) for the determination of angiotensin II in plasma (EDTA). For research use only, not for use in diagnostic procedures. | The Complement C4d assay is an enzyme-linked immunosorbent assay (ELISA) for the semiquantitative determination of C4d in human plasma. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay (ELISA) for the determination of Insulin in serum and plasma. FDA exempt, can be used for in-vitro diagnostics. | Enzyme immunoassay (ELISA) for the determination of Sex-Hormone-Binding Globulin (SHBG) in serum and heparin plasma. For research use only, not for use in diagnostic procedures. |
| Detection Target | Normetanephrine | GPIHBP1 Autoantibody | Phospho Tau (181P) | Echinococcus IgG | Dopamine |
| Sample Type | Blood Plasma | Serum, EDTA-plasma, heparin plasma, and post-heparin EDTA-plasma. | Cerebrospinal fluids | Serum and plasma (citrate, heparin). | Blood Plasma, Urine |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Radio Immuno Assay (RIA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Detection Range | 0 / 2.2 - 143 pg/mL | 4.7 to 150.0 pmol/L | 0 / 5 - 400 ng/mL | 6.25 to 100 µIU/mL | 4 to 260 nmol/L |
| Sensitivity | 23 pg/mL | 0.001 U/mL | 1.9 pg/mL | 97.22% (95% confidence interval: 85.47% - 99.93%) | Urine: 2.5 ng/mL. Plasma: 49.0 pg/mL. |
| Assay Time | Overnight + 1 hour (incubation) | 18 hrs 15 mins (incubation) | 2 hours total incubation time. | 1 hr 15 mins (incubation) | 1 hr (incubation) |
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