|  | | | | |
| Company | IBL-America | IBL-America | IBL-America | IBL-America | IBL-America |
| Item | Histamine ELISA | C5a ELISA Assay | Calcitonin ELISA Assay | Insulin-like Growth Factor-II (IGF-II) ELISA | Phospho Tau (181P) ELISA |
| Citations | | | | | |
| Catalog Number | IB89128R | IB79153 | BM7024 | E30 | 27812 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Enzyme Immunoassay for the determination of Histamine in plasma and urine. In combination with the supplementary kit (IB89145), the assay is performed for the histamine release in heparinized whole blood. For research use only, not for use in diagnostic procedures. | Enzyme immunoassay for the determination of Anaphylatoxin C5a in human plasma or urine. For research use only, not for use in diagnostic procedures. | Enzyme-linked immunosorbent assay (ELISA) for the determination of Calcitonin in human serum. This assay is intended for in vitro diagnostic use. | Enzyme immunoassay (ELISA) for the determination of IGF-II in human serum, plasma, urine, saliva, and cell culture supernatants. For research use only, not for use in diagnostic procedures. | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More |
| Detection Target | Histamine | DPP4 / CD26 | 25-hydroxyvitamin D2 and D3 (25OH-D2 and 25OH-D3) | Corynebacterium diphtheriae toxin IgG | Normetanephrine |
| Sample Type | Plasma and urine. Whole blood may be used with supplementary Histamine (Release) kit, catalog # IB89145. Please see protocol for more information. | Serum, Blood Plasma, Urine, CSF | Serum | Serum, Blood Plasma | Blood Plasma |
| Method | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) | Enzyme-Linked Immunosorbent Assay (ELISA) |
| Detection Range | 0 / 0.5 - 50 ng/mL | 0.1 to 10 µg/L | 10 to 300 pg/mL | 0.45 to 9.00 ng/mL | 0 / 2.2 - 143 pg/mL |
| Sensitivity | Plasma: 0.12 ng/mL; Urine: 0.30 ng/mL. | 8.58 pg/mL | 3.35 ng/mL | 100% (95% confidence interval: 95.44% - 100%) | 23 pg/mL |
| Assay Time | 45 min. incubation (RT) + 15 min. (RT) + 3 hours (RT) + 30 min. (RT) + 30 min. (RT) = 5 hours total incubation time. | 50 mins (incubation) | 4 hrs 30 mins (incubation) | 3 hrs (incubation) | Overnight + 1 hour (incubation) |
| Get Quote | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |