| Description | Radioimmunoassay (RIA) for the determination of human 17ß-Estradiol (E2) in serum. FDA registered 510(k) Exempt. For In-Vitro Diagnostic Use. | Solid phase sandwich ELISA for the determination of human Aß molecules which bind to nti-human Aß (N) (82E1) mouse MoAb with two or more epitopes (oligomers, polymers with a protein etc.) in serum, EDTA-plasma and brain tissue extract. For research use only, not for use in diagnostic procedures. | Solid phase sandwich ELISA for the determination of human Endothelial Lipase (EL) in serum, EDTA-plasma and cell culture supernatant. For research use only, not for use in diagnostic procedures. | Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (Tau protein is a 45-50kDa microtubule-associated protein which consists of 352-441 amino acids. It has a role of stabilizing microtubules that transport intracellular substances in nerve cells. It is known that tauopathy such as Alzheimer's type dementia (AD) and frontotemporal lobar degeneration (FTLD) is developed due to abnormal accumulation of Tau. Three features of AD, senile plaque, neurofibrillary tangle and neuronal cell death have been observed in the brain of AD subjects and it is considered that neurofibrillary tangle is triggered by abnormal accumulation of Tau. The main element of neurofibrillary tangle is called PHF (paired helical filament) and it is accumulated in nerve cells. Overexpressed phosphorylated tau is aggregated and it becomes a main cause of PHF. It has been thought that GSK-3ß is involved in the process of phosphorylation of tau and Aß promotes the activity for phosphorylation of tau. It has been observed that the concentration of Tau is very high in CSF of subjects with neurodegenerative diseases such as Alzheimer's disease as it is released in CSF due to neuron is destroyed while it is rarely detected in CSF of healthy subjects. This ELISA is for the determination of human phosphorylated Tau (181) in CSF. For research use only, not for use in diagnostic procedures.... Read More | Solid phase sandwich ELISA for the determination of Human Tenascin-C containing high molecular weight variants (Human Tenascin-C HMWV) in serum, plasma (heparin), or cell culture media. For research use only, not for use in diagnostic procedures. |