HPLC Pump / Solvent Delivery System

When delivering smaller particles through the liquid mobile phase of a HPLC unit, the liquid must be forced through the column under pressure. The purpose of an HPLC pump, also called a solvent delivery system, is to force the liquid through the system while maintaining a specific flow rate. HPLC pumps can be broadly categorized into three types: syringe pumps that provide pulseless delivery, reciprocating or piston pumps that push the mobile phase through with a series of pistons, and pneumatic pumps that use gas to pressurize the mobile phase. Reciprocating pumps are most common due to their good pressure generation, constant flow rate, and small footprint, but each type of pump has its pros and cons that should be weighed when purchasing. Other things to look out for when selecting a pump include the instrument’s compatibility with different solvents, low dead volume to minimize issues with solvent changeover, delivery method (either isocratic or gradient), as well as things like price, ease of use, and lifetime.
CompanyJASCOJASCOJASCOJASCOJASCO
ItemPU-4200 Series HPLC PumpsPU-4000 Series HPLC PumpsPU-4100 Series HPLC PumpsPU-4300 Series HPLC PumpsPU-4500 Series HPLC Pumps
Citations
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(8)
(7)
Catalog NumberPU-4285PU-4080i / PU-4086 / PU-4087 / PU-4088PU-4180 / PU-4185PU-4380 / PU-4386 / PU-4387 / PU-4388PU-4580 / PU-4585 / PU-4586 / PU-4587
Price
DescriptionThe PU-4200 Series HPLC Pumps are used for conventional HPLC, RHPLC, and UHPLC applications with a max pressure of 1,300 bar (130 MPa).

The last two digit of pump model name, i.e. PU-4280/85/86/87/88 represents each of flow-rate ranges:
  • 80: up to 10 mL/min (conventional to semi-prep, up to 10 mm
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The PU-4000 Series HPLC Pumps are used for conventional pressure applications in HPLC with a max pressure of 500 bar (50 MPa).

The last two digit of pump model name, i.e. PU-4080/86/87/88 represents each of flow-rate ranges:
  • 80: up to 10 mL/min (conventional to semi-prep, up to 10 mm I.D. column
... Read More
The PU-4100 Series HPLC Pumps are used for conventional HPLC and RHPLC applications with a max pressure of 700 bar (70 MPa).

The last two digit of pump model name, i.e. PU-4180/85/86/87/88 represents each of flow-rate ranges:
  • 80: up to 10 mL/min (conventional to semi-prep, up to 10 mm I.D.
... Read More
The PU-4300 Series HPLC Pumps are used for analytical and preparative Supercritical Fluid Chromatography (SFC) with a max pressure of 500 bar (50 MPa).

The last two digit of pump model name, i.e. PU-4380/85/86/87/88 represents each of flow-rate ranges:
  • 80: up to 10 mL/min (conventional to semi-
... Read More
The PU-4500 Series HPLC Pumps are used for compact HPLC systems with a max pressure of 500 bar (50 MPa).

The last two digit of pump model name, i.e. PU-4580/85/86/87/88 represents each of flow-rate ranges:
  • 80: up to 10 mL/min (conventional to semi-prep, up to 10 mm I.D. column)
  • 85: up to 4 mL/
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TypeHPLC, RHPLC, and UHPLC PumpsHPLC and Preparative HPLC PumpsHPLC and RHPLC PumpsSFC (Analytical and Preparative) PumpsCompact HPLC Pumps
Flow RatePU-4285: up to 4 mL/min (semi-micro to conventional, 1.5 to 4.6 mm I.D. column)PU-4080i: up to 10 mL/min (conventional to semi-prep, up to 10 mm I.D. column)
PU-4086: up to 20 mL/min (conventional to semi-prep, up to 20 mm I.D. column)
PU-4087: up to 50 mL/min (to semi-prep, 20 to 30 mm I.D. column)
PU-4088: up to 150 mL/min (up to prep, from 20 to 50 mm I.D. column, up to 30 mm I.D. SFC column)
PU-4180: up to 10 mL/min (conventional to semi-prep, up to 10 mm I.D. column)
PU-4185: up to 4 mL/min (semi-micro to conventional, 1.5 to 4.6 mm I.D. column)
PU-4380: up to 10 mL/min (conventional to semi-prep, up to 10 mm I.D. column)
PU-4386: up to 20 mL/min (conventional to semi-prep, up to 20 mm I.D. column)
PU-4387: up to 50 mL/min (to semi-prep, 20 to 30 mm I.D. column)
PU-4388: up to 150 mL/min (up to prep, from 20 to 50 mm I.D. column, up to 30 mm I.D. SFC column)
PU-4580: 0.5 µL to 10 mL/min
PU-4585: 0.05 to 4 mL/min
PU-4586: 0.5 to 20 mL/min
PU-4587: 5 to 40 mL/min
Max. Pressure1,300 Bar (130 MPa)PU-4080i: 250 Bar (25 MPa)
PU-4086/4087/4088: 500 Bar (50 MPa)
700 Bar (70 MPa)500 Bar (50 MPa)PU-4580: 50 MPa from 0.5 µL to 6 mL/min / 35 MPa from 6 mL/min to 10 mL/min
PU-4585: 50 Mpa from 0.05 to 3 mL/min / 35 MPa from 3 to 4 mL/min
PU-4586: 50 MPa from 0.5 to 10 mL/min / 40 MPa from 10 to 15 mL/min / 25 MPa from 15 to 20 mL/min
PU-4587: 15 MPa
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