Liquid Handling Robotics (Automated Systems)

• Designed for biochemical and genomic sample and reagent transfer
• Improve data quality while saving on reagent costs
• Reagent reservoir for larger volume reagent transfers

• Highly precise and accurate low volume

• Designed for biochemical and genomic sample and reagent transfer
• Improve data quality while saving on reagent costs
• Reagent reservoir for larger volume reagent transfers

• Highly precise and accurate low volume transfers enabling assay miniaturization
• Builds assays 50–100 times faster than traditional liquid handlers giving the lab higher capacity from one instrument
• Suite of Echo Software Applications guide creation of complex protocols for a variety of applications
• Eliminates pipetting variances that affect assay success
• Integrates into the Labcyte Access Laboratory Workstation for increased throughput

The flexibility, speed, accuracy, and precision of the Echo 525 Liquid Handler enable researchers to build assays that are not possible with traditional liquid handlers. The use of acoustic sound energy removes the traditional boundaries of tip and pin tool based liquid handlers. Transfer variable fluid heights and viscosities from one source plate to enable rapid assay creation in one fluid transfer run. Say goodbye to fixed plate designs as the Echo Liquid Handler moves fluids from any well to any well enabling researchers to design the experimental plates they need to make new discoveries.

Assay assembly and the transfer of one reagent to many wells is simplified using the Echo Qualified Reservoir. With the capability of transferring up to 2.5 µL from each micro-well, you can build your assay without requiring an instrument change – saving time and money.

The Echo 525 Liquid Handler transfers a wide range of fluids during one transfer including distilled water, buffers, nucleic acids, and reagents containing up to 50% glycerol. With its versatile fluid range, transfer volume range, any well to any well transfer capability, and powerful applications software the Echo 525 Liquid Handler supports a wide range of genomic assay workflows:

• Gene Synthesis
• PCR and qPCR assay set-up
• RNA and DNA NGS sequencing workflows
• Sanger sequencing assay set-up
• Single-cell sample preparation

Perform online cultivation experiments and prepare media compositions with the BioLector XT microbioreactor & Biomek i5 liquid handler integration. Our unique automated screening platform for microbial cultures allows you to

Perform online cultivation experiments and prepare media compositions with the BioLector XT microbioreactor & Biomek i5 liquid handler integration. Our unique automated screening platform for microbial cultures allows you to design and execute highly elaborate experiments that are on track with biological signals increasing the experiment reproducibility. Individually triggered sampling, dosing actions (e.g., adding inducer or feed solutions), or inoculation of culture wells in the BioLector XT microplate are executed on the basis of the online, real-time signals from the BioLector XT microbioreactor (biomass, pH value, dissolved oxygen concentration, experiment time, etc.) without the need to stop the shaking of the microplate inside the BioLector XT instrument.

• Measure biomass, pH value, dissolved oxygen and fluorescence online
• Increased walk-away time
• Reduce potential contamination with automation
• Reliable scale-up to benchtop fermenters
• Reproducibility and scalability of results

The system automatically draws samples, adds media and inducer solutions or inoculates the culture wells triggered by experiment time or BioLector XT microbioreactor online signals. This allows for an increased walk-away time while keeping the same level of quality output.

Take advantage of the integrated system to transform your workflow and get reproducible experiment data. The scalable results make it fast and easy to bring more products to market.

Incorporating cultivation modes with online triggers (real-time signals from the BioLector XT microbioreactor), you get the benefits of continuous operation 24/7.

Fixed Biomek tips are cleaned and decontaminated between actions reducing the potential for cross-contamination.

• Maximizing performance and versatility in a compact footprint
• Confidence in your data, powered by accurate and flexible pipetting
• No automation expertise required
• Seamless adaptation to your existing workflows
• Comfort and safe operation

• 15 ANSI/SLAS standard pipettable and 5 flex deck positions
• Includes 12 standard and 3 short static automated labware positioners (ALPs)
• Ready for on-deck and off-deck integration (left, right, back & down)
• 8-channel pipetting pod allows selective loading of 1–8 tips in any sequence
• Gripper supports labware up to 12.8 cm in height and 725 g in weight
• Uses standard Biomek i-Series 96-format disposable tips
• Windows® 11-compatible Biomek Software with touchscreen support
• Secure remote diagnostics and troubleshooting enabled
• Deck observation system
• Installed UV-C light
• Positive or negative pressure HEPA-filtration (optional)
• Supports 21 CFR Part 11 with user accounts, permissions, and audit trails

• Access to MyBeckmanLearning eLearning Repository
• Virtual courses or in-person training
• Welcome package that includes:
  • Installation
  • 3 Learner Licenses for MyBeckmanLearning
  • Basic on-site operator training by field service engineer
  • Instrument relocation within the first year
  • ~50% coverage for a single accidental damage due to user error
  • Remote service support
  • Priority response over Warranty users

• Measure DMSO hydration levels to gain insights into sample integrity and improve transfer quality
• Elimination of compound loss, cross-contamination, carryover, or leachates through non-contact transfer
• Accurate and precise transfer of

• Measure DMSO hydration levels to gain insights into sample integrity and improve transfer quality
• Elimination of compound loss, cross-contamination, carryover, or leachates through non-contact transfer
• Accurate and precise transfer of nanoliter-scale quantities, enabling assay miniaturization, further reducing costs
• Better results through direct dilution of compounds, an improvement over serial dilution methods
• Flexibility to transfer any volume of liquid from any source well to any destination well

The FluidX AcoustiX Sample Tube (FAST) was developed in collaboration with and is sold by Brooks Life Sciences for ultra-high-density sample storage. The acoustic tube offers the following benefits:

• Echo Qualified design - compatible with Echo 650T and 655T Liquid Handlers
• Preserves sample integrity from storage to screen
• Miniaturize upstream liquid handling steps to conserve sample
• Rapidly pick sets of samples for targeted screening

To meet the broad spectrum of sample throughput needs, Echo 650 Series Liquid Handlers seamlessly integrate with the highly configurable Access™ Dual Robot System accommodating a wide variety of devices and enabling a fully automated workflow.

• Configured to achieve optimal throughput for sample management workflows
• Compact and ergonomic design with docking modules, turntables, retractable shelves, and drawers
• Optional features can include environmental management to protect samples from hydration or evaporation

The Echo 655T Liquid Handler supports sample transfer directly from Echo Qualified sample tubes, enabling a fully non-contact liquid handling workflow from sample storage all the way to assay ready plates. The Echo 655T Liquid Handler is capable of transferring as little as 2.5 nL from 384-well and 1536-well microplates, and now, from sample tubes arrayed in a 96-tube format. Additionally, it transfers at the highest speed to meet the needs of high-thoughput biochemical and cell-based screening.

PAT700 Total Organic Carbon (TOC) Analyzers are specifically designed to help demonstrate compliance to the pharmacopoeial requirements for TOC and conductivity for Purified Water and Water For Injection.

• TOC, Uncompensated Conductivity and Temperature from just one

PAT700 Total Organic Carbon (TOC) Analyzers are specifically designed to help demonstrate compliance to the pharmacopoeial requirements for TOC and conductivity for Purified Water and Water For Injection.

• TOC, Uncompensated Conductivity and Temperature from just one analyzer – can be fully calibrated and validated to USP<643> and USP<645>
• Low cost of ownership – 12 month service and calibration intervals
• Root-cause analysis support – water sample automatically taken if there is a TOC excursion
• All SOPs are pre-loaded into the PAT700, leading users step-by step with on-screen pictures and prompts

• 12 month service intervals supported by auto-switching Main and Standby UV oxidation lamps with UV output monitoring
• No chemicals/reagents required – PAT700 just uses strong UV lamps to oxidize TOC
• No peristaltic pump tubing or pump heads to replace – PAT700 uses water system pressure to push sample into measurement cell for analysis

• User can pre-program the PAT700 so that at a pre-determined TOC level, it will capture a water sample which can then be later analyzed in the QC Lab to assist root cause analysis should a TOC excursion be detected
• On-board grab sampler allows the user to take samples from different locations/use points to support root cause analysis

• PAT700 can be fully calibrated and validated for compliance to USP<643> for TOC and USP<645> for conductivity
• Complete oxidation to EP 2.2.44 requirements – the PAT700 ensures complete TOC oxidation through oxidation dynamic end-point detection
• 21CFR part 11 support – everyday users can view TOC and Conductivity results as a Guest without the ability to make any changes to the PAT700. Initial configuration and subsequent changes are protected through multi-level user name and password protection
• Dual-stream version available to demonstrate compliance both at the start and end of water loops simultaneously

• All SOPs are pre-loaded into the PAT700, leading users step-by step with on-screen pictures and prompts
• All Calibration and System Suitability standards come with certified value data and use by dates programmed into an RFID tag on the bottle itself. Following the on-screen SOPs the user is prompted to load the bottles and the PAT700 then reads the RFID tags on the bottles. If the bottles have been loaded in the wrong order, or if they have expired the PAT700 provides a warning on the touch-screen. The PAT700 then uploads certified values, carries out the test and automatically calculates a pass/fail result and provides a report.