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| Company | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences |
| Item | PAT700 TOC Analyzers | BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration | Biomek i3 Benchtop Liquid Handler | Cydem VT Automated Clone Screening System | OptiMATE Gradient Maker for Density Gradient Centrifugation Sample Preparation |
| Catalog Number | PAT700 | BioLector XT + Biomek i5 | Biomek i3 | Cydem VT | OptiMATE |
| Price | | | | | |
| Description | PAT700 TOC Analyzer Overview
PAT700 Total Organic Carbon (TOC) Analyzers are specifically designed to help demonstrate compliance to the pharmacopoeial requirements for TOC and conductivity for Purified Water and Water For Injection. - TOC, Uncompensated Conductivity and Temperature from just one
PAT700 TOC Analyzer Overview
PAT700 Total Organic Carbon (TOC) Analyzers are specifically designed to help demonstrate compliance to the pharmacopoeial requirements for TOC and conductivity for Purified Water and Water For Injection. - TOC, Uncompensated Conductivity and Temperature from just one analyzer – can be fully calibrated and validated to USP<643> and USP<645>
- Low cost of ownership – 12 month service and calibration intervals
- Root-cause analysis support – water sample automatically taken if there is a TOC excursion
- All SOPs are pre-loaded into the PAT700, leading users step-by step with on-screen pictures and prompts
PAT700 TOC Analyzer Features
Low cost of ownership
- 12 month service intervals supported by auto-switching Main and Standby UV oxidation lamps with UV output monitoring
- No chemicals/reagents required – PAT700 just uses strong UV lamps to oxidize TOC
- No peristaltic pump tubing or pump heads to replace – PAT700 uses water system pressure to push sample into measurement cell for analysis
Root-cause analysis support
- User can pre-program the PAT700 so that at a pre-determined TOC level, it will capture a water sample which can then be later analyzed in the QC Lab to assist root cause analysis should a TOC excursion be detected
- On-board grab sampler allows the user to take samples from different locations/use points to support root cause analysis
Improved compliance
- PAT700 can be fully calibrated and validated for compliance to USP<643> for TOC and USP<645> for conductivity
- Complete oxidation to EP 2.2.44 requirements – the PAT700 ensures complete TOC oxidation through oxidation dynamic end-point detection
- 21CFR part 11 support – everyday users can view TOC and Conductivity results as a Guest without the ability to make any changes to the PAT700. Initial configuration and subsequent changes are protected through multi-level user name and password protection
- Dual-stream version available to demonstrate compliance both at the start and end of water loops simultaneously
Reduced training burden – no manual calculations/data entry
- All SOPs are pre-loaded into the PAT700, leading users step-by step with on-screen pictures and prompts
- All Calibration and System Suitability standards come with certified value data and use by dates programmed into an RFID tag on the bottle itself. Following the on-screen SOPs the user is prompted to load the bottles and the PAT700 then reads the RFID tags on the bottles. If the bottles have been loaded in the wrong order, or if they have expired the PAT700 provides a warning on the touch-screen. The PAT700 then uploads certified values, carries out the test and automatically calculates a pass/fail result and provides a report.
... Read More | BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration
Perform online cultivation experiments and prepare media compositions with the BioLector XT microbioreactor & Biomek i5 liquid handler integration. Our unique automated screening platform for microbial cultures allows you to BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration
Perform online cultivation experiments and prepare media compositions with the BioLector XT microbioreactor & Biomek i5 liquid handler integration. Our unique automated screening platform for microbial cultures allows you to design and execute highly elaborate experiments that are on track with biological signals increasing the experiment reproducibility. Individually triggered sampling, dosing actions (e.g., adding inducer or feed solutions), or inoculation of culture wells in the BioLector XT microplate are executed on the basis of the online, real-time signals from the BioLector XT microbioreactor (biomass, pH value, dissolved oxygen concentration, experiment time, etc.) without the need to stop the shaking of the microplate inside the BioLector XT instrument. - Measure biomass, pH value, dissolved oxygen and fluorescence online
- Increased walk-away time
- Reduce potential contamination with automation
- Reliable scale-up to benchtop fermenters
- Reproducibility and scalability of results
BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration Features
Automation
The system automatically draws samples, adds media and inducer solutions or inoculates the culture wells triggered by experiment time or BioLector XT microbioreactor online signals. This allows for an increased walk-away time while keeping the same level of quality output. Reproducibility and Scalability
Take advantage of the integrated system to transform your workflow and get reproducible experiment data. The scalable results make it fast and easy to bring more products to market. Software
Incorporating cultivation modes with online triggers (real-time signals from the BioLector XT microbioreactor), you get the benefits of continuous operation 24/7. Reduce Contamination Risk
Fixed Biomek tips are cleaned and decontaminated between actions reducing the potential for cross-contamination. ... Read More | Smart. Small. Powerful.
The Biomek i3 Benchtop Liquid Handler is the most compact member of the Biomek i-Series family, designed to enhance entry-level to medium-throughput workflows. If you're just starting your journey into lab automation or need a simple, cost-effective, yet highly capable Smart. Small. Powerful.
The Biomek i3 Benchtop Liquid Handler is the most compact member of the Biomek i-Series family, designed to enhance entry-level to medium-throughput workflows. If you're just starting your journey into lab automation or need a simple, cost-effective, yet highly capable alternative to more complex systems, the Biomek i3 is an excellent choice.
Biomek i3 Liquid Handler Benefits - Maximizing performance and versatility in a compact footprint
- Confidence in your data, powered by accurate and flexible pipetting
- No automation expertise required
- Seamless adaptation to your existing workflows
- Comfort and safe operation
Biomek i3 Liquid Handler Key Features - 15 ANSI/SLAS standard pipettable and 5 flex deck positions
- Includes 12 standard and 3 short static automated labware positioners (ALPs)
- Ready for on-deck and off-deck integration (left, right, back & down)
- 8-channel pipetting pod allows selective loading of 1–8 tips in any sequence
- Gripper supports labware up to 12.8 cm in height and 725 g in weight
- Uses standard Biomek i-Series 96-format disposable tips
- Windows® 11-compatible Biomek Software with touchscreen support
- Secure remote diagnostics and troubleshooting enabled
- Deck observation system
- Installed UV-C light
- Positive or negative pressure HEPA-filtration (optional)
- Supports 21 CFR Part 11 with user accounts, permissions, and audit trails
Quick Onboarding Options - Access to MyBeckmanLearning eLearning Repository
- Virtual courses or in-person training
- Welcome package that includes:
- Installation
- 3 Learner Licenses for MyBeckmanLearning
- Basic on-site operator training by field service engineer
- Instrument relocation within the first year
- ~50% coverage for a single accidental damage due to user error
- Remote service support
- Priority response over Warranty users
... Read More | The Cydem VT Automated Clone Screening System combines multiple trusted Beckman Coulter technologies into one advanced platform that empowers lab managers with a far more effective, high-throughput method—offering increased confidence that promising clones don’t get overlooked in the process of The Cydem VT Automated Clone Screening System combines multiple trusted Beckman Coulter technologies into one advanced platform that empowers lab managers with a far more effective, high-throughput method—offering increased confidence that promising clones don’t get overlooked in the process of consistently selecting the best.
- High-throughput clone screening in cell line development
- Automated, walk-away operation
- All results in one software
- pH-controlled fed-batch cultivation of 96 parallel clones with individual gassing
- On-deck cell count, viability and antibody titer analysis
- Fully integrated system
... Read More | The OptiMATE Gradient Maker automates the preparation of density gradients for ultracentrifugation. Density gradient ultracentrifugation is a gradient-based purification system that provides precise purification of samples based on their differences in particle loading or densities. This system:
The OptiMATE Gradient Maker automates the preparation of density gradients for ultracentrifugation. Density gradient ultracentrifugation is a gradient-based purification system that provides precise purification of samples based on their differences in particle loading or densities. This system:
- Provides a software interface for creating a density gradient profile and layering samples
- Optimizes density gradient dispensing to reduce centrifugation time
- Automatically and rapidly dispenses a precise density gradient tube
- Automates the sealing of Beckman Coulter Quick-Seal centrifuge tubes
... Read More |
| Volume | Inquire | Volume (cultivation well) 800 to 2400 µL (depending on microtiter plate type) | 1 to 1,000 µL | Inquire | 13.5, 39, and 94 mL tubes |
| Applications | Demonstrate compliance with the pharmacopoeial requirements for TOC and conductivity for Purified Water and Water For Injection | Automated sampling/harvesting, automated inoculation of cultivation wells, automated induction, bolus feeding / repeated fed-batch, induction profiling, microbial growth synchronization, feed profiling, media preparation, and automated upstream processing with microbial cultures | Cell transfection, nucleic acid extraction, ELISA, NGS library prep, plasmid DNA prep, antibody cocktailing, mass spec sample prep, cell passaging/media exchange, PCR/qPCR setup, AMPure XP cleanup, SPRIselect size selection, Valita Titer assay | Top clone screening in Cell Line Development | Density Gradient Centrifugation Sample Preparation |
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