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| Company | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences | Beckman Coulter Life Sciences |
| Item | OptiMATE Gradient Maker for Density Gradient Centrifugation Sample Preparation | BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration | Cydem VT Automated Clone Screening System | RoboLector Platform | TQ-Prep Workstations |
| Catalog Number | OptiMATE | BioLector XT + Biomek i5 | Cydem VT | RoboLector | TQ-Prep |
| Price | | | | | |
| Description | The OptiMATE Gradient Maker automates the preparation of density gradients for ultracentrifugation. Density gradient ultracentrifugation is a gradient-based purification system that provides precise purification of samples based on their differences in particle loading or densities. This system:
The OptiMATE Gradient Maker automates the preparation of density gradients for ultracentrifugation. Density gradient ultracentrifugation is a gradient-based purification system that provides precise purification of samples based on their differences in particle loading or densities. This system:
- Provides a software interface for creating a density gradient profile and layering samples
- Optimizes density gradient dispensing to reduce centrifugation time
- Automatically and rapidly dispenses a precise density gradient tube
- Automates the sealing of Beckman Coulter Quick-Seal centrifuge tubes
... Read More | BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration
Perform online cultivation experiments and prepare media compositions with the BioLector XT microbioreactor & Biomek i5 liquid handler integration. Our unique automated screening platform for microbial cultures allows you to BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration
Perform online cultivation experiments and prepare media compositions with the BioLector XT microbioreactor & Biomek i5 liquid handler integration. Our unique automated screening platform for microbial cultures allows you to design and execute highly elaborate experiments that are on track with biological signals increasing the experiment reproducibility. Individually triggered sampling, dosing actions (e.g., adding inducer or feed solutions), or inoculation of culture wells in the BioLector XT microplate are executed on the basis of the online, real-time signals from the BioLector XT microbioreactor (biomass, pH value, dissolved oxygen concentration, experiment time, etc.) without the need to stop the shaking of the microplate inside the BioLector XT instrument. - Measure biomass, pH value, dissolved oxygen and fluorescence online
- Increased walk-away time
- Reduce potential contamination with automation
- Reliable scale-up to benchtop fermenters
- Reproducibility and scalability of results
BioLector XT Microbioreactor & Biomek i5 Liquid Handler Integration Features
Automation
The system automatically draws samples, adds media and inducer solutions or inoculates the culture wells triggered by experiment time or BioLector XT microbioreactor online signals. This allows for an increased walk-away time while keeping the same level of quality output. Reproducibility and Scalability
Take advantage of the integrated system to transform your workflow and get reproducible experiment data. The scalable results make it fast and easy to bring more products to market. Software
Incorporating cultivation modes with online triggers (real-time signals from the BioLector XT microbioreactor), you get the benefits of continuous operation 24/7. Reduce Contamination Risk
Fixed Biomek tips are cleaned and decontaminated between actions reducing the potential for cross-contamination. ... Read More | The Cydem VT Automated Clone Screening System combines multiple trusted Beckman Coulter technologies into one advanced platform that empowers lab managers with a far more effective, high-throughput method—offering increased confidence that promising clones don’t get overlooked in the process of The Cydem VT Automated Clone Screening System combines multiple trusted Beckman Coulter technologies into one advanced platform that empowers lab managers with a far more effective, high-throughput method—offering increased confidence that promising clones don’t get overlooked in the process of consistently selecting the best.
- High-throughput clone screening in cell line development
- Automated, walk-away operation
- All results in one software
- pH-controlled fed-batch cultivation of 96 parallel clones with individual gassing
- On-deck cell count, viability and antibody titer analysis
- Fully integrated system
... Read More | RoboLector Platform Overview
The RoboLector XL system is an automated fermentation platform which combines the high-throughput fermentation and online monitoring capability of the BioLector XT microbioreactor with the precise and accurate liquid handling of a robotic system.
The RoboLector system RoboLector Platform Overview
The RoboLector XL system is an automated fermentation platform which combines the high-throughput fermentation and online monitoring capability of the BioLector XT microbioreactor with the precise and accurate liquid handling of a robotic system.
The RoboLector system autonomously prepares media compositions, among others, from the design of experiments (DoE) tests, followed by an online-monitored high-throughput cultivation.
Furthermore, pH adjustments can be made and inducers as well as feed solutions can be added to each cultivation well according to a pre-defined schedule or triggered by online process signals. Automated sampling into various targets including a cooling station facilitates optimal process monitoring and control.
Features of the RoboLector XL
Cultivation Modes - DO or time controlled feeding
- Fed-batch with bolus feeding
- Repeated fed-batch
- Biomass dependent sampling or dosing
- Time dependent sampling or dosing
- pH adjustments
Online Trigger Signals - Biomass concentration
- pH, DO (using optodes)
- Fluorescent molecules (GFP, YFP, DsRed ...)
- NAD(P)H and riboflavins
- Process or induction time
- Working volume
Advantages - Automated upstream processing of up to 48 parallel cultivations
- Continuous operation 24 hours/day and 7 days/week
- Plug & Play disposable technology
- Design of experiments (DoE)• Detailed process understanding in short time
- Excellent pipetting accuracy (< 5 %, 50 - 950 µl) and reproducibility (CV < 5 %, 50 - 950 µl)
- Reliable scale-up to lab-fermenters
- Fast and easy data analysis
- A valuable tool for PAT and QbD
- Processing units possible (for custom made solutions)
Applications - Automated sampling
- Automated induction
- Induction profiling
- Synchronized process manipulation
- pH profiling
- Feeding profiling
- Media preparation
- Process characterization
- High-throughput protein expression
- Automated upstream processing with microbial cultures
... Read More | Proven Performance and Reliability
The TQ-Prep Workstation delivers whole blood lysis cell preparations for your flow cytometry needs time after time. A standard 32-tube carousel allows walk-away processing and perfectly complements our Navios EX flow cytometer. The IMMUNOPREP Reagent System with Proven Performance and Reliability
The TQ-Prep Workstation delivers whole blood lysis cell preparations for your flow cytometry needs time after time. A standard 32-tube carousel allows walk-away processing and perfectly complements our Navios EX flow cytometer. The IMMUNOPREP Reagent System with ready-to-use CYTO-STAT tetraCHROME Monoclonal Antibody Reagents provides fast no-wash sample preparations for flow cytometric analysis, while maintaining cellular integrity and morphology. - True walkaway operation from onboard incubation and lysis cycle processing
- User-friendly interface with a larger icon-driven touchscreen
- Maximum reliability with minimal maintenance
- The vortex system mixing ensures reproducible homogenous cell lysis
- Reagent dispensing with syringe pump system consistently provides precise and accurate volumes
- Sample throughput of up to 32 samples in only 24 minutes
- Windows 10 IOT (Internet of things) Enterprise LTSC Operating System
- Data transfer via USB
Features
The TQ-Prep Workstation and IMMUNOPREP Reagent System together provide rapid, no-wash whole-blood sample preparation. Automation provides inter-sample and inter-laboratory consistency and reproducibility. Workflow
- Reduced number of repeat samples for cost & labor efficiencies
- Sample throughput of up to 32 samples in 24 minutes
Reliability
- Maximum reliability with minimal maintenance
- Continuous real-time feedback allowing operators to follow incubation & lysing processes
Performance
- Onboard incubation and lysis cycle processing for walkaway operation
- Advanced syringe pump system for precise & accurate reagent dispensing
TQ-Prep Upgraded
- Updated covers for front panel and reagent cover with improved fit
- Data privacy and security enhancements
- Updated safety certificates
- The touch screen interface has been replaced with a capacitive touch display interface
- Display icons have been resized for larger display
... Read More |
| Volume | 13.5, 39, and 94 mL tubes | Volume (cultivation well) 800 to 2400 µL (depending on microtiter plate type) | Inquire | Inquire | Inquire |
| Applications | Density Gradient Centrifugation Sample Preparation | Automated sampling/harvesting, automated inoculation of cultivation wells, automated induction, bolus feeding / repeated fed-batch, induction profiling, microbial growth synchronization, feed profiling, media preparation, and automated upstream processing with microbial cultures | Top clone screening in Cell Line Development | Automated sampling, automated induction, induction profiling, synchronized process manipulation, pH profiling, feeding profiling, media preparation, process characterization, high-throughput protein expression, and automated upstream processing with microbial cultures | Automated no-wash whole-blood sample preparation |
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