Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemVanquish™ Flex Binary UHPLC SystemThermo Scientific Vanquish Inverse Gradient LC SystemThermo Scientific Vanquish Neo UHPLC SystemThermo Scientific™ Transcend™ TLX UHPLC SystemsVanquish™ Horizon UHPLC System
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Catalog NumberIQLAAAGABHFAPUMBJCIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMBMPIQLAAEGACWFAKWMZZZIQLAAAGABHFAPUMZZZ
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DescriptionThe Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, ... Read MoreOur portfolio of innovative and dependable liquid chromatography (LC) instruments includes analytical HPLC and UHPLC systems to handle any separation challenge from simple to complex samples; application-specific HPLC and UHPLC systems for applications such as 2D-LC and dual LC; and nano-, capillary... Read MoreFor researchers pursuing the next scientific breakthrough, the Vanquish Neo UHPLC system delivers maximum performance 24/7 for nano, capillary, and micro-flow LC-MS. Thermo Scientific™ ProFlow™ XR 1500 bar pump technology ensures excellent retention time precision from nano-flow up to 100 µL/min, ... Read MoreEnable fast cleanup of complex matrices for accelerated online sample preparation, lower your laboratory costs, and improve data quality using Thermo Scientific Transcend TLX Systems with TurboFlow technology. These systems use a combination of chromatographic techniques for online sample cleanup to... Read MoreThe Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read More
QuantityEAEAEAEAEA
Flow Rate8 mL/minInquireInquireInquire8 mL/min
Max. Pressureup to 1000 bar (15,000psi)InquireInquireInquireUp to 1500 bar (22,000 psi)
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